Structure of PDB 5nx5 Chain A

Receptor sequence
>5nx5A (length=287) Species: 1901 (Streptomyces clavuligerus) [Search protein sequence]
RVSPDLARARARHLDWVHAMDLVRGEEARRRYEFSCVADIGAYGYPHATG
ADLDLCVDVLGWTFLFDDQFDRERDALAVCAELTDLLWKGTAATAASPPI
VVAFSDCWERMRAGMSDAWRRRTVHEWVDYLAGWPTKLADRAHGAVLDPA
AHLRARHRTICCRPLFALAERVGGYEVPRRAWHSSRLDGMRFTTSDAVIG
MNELHSFEKDRAQHANLVLSLVHHGGLTGPEAVTRVCDLVQGSIESFLRL
RSGLPELGRALGVEGAVLDRYADALSAFCRGYHDWGR
3D structure
PDB5nx5 Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase.
ChainA
Resolution1.82 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T75 F76 D79 D83 R157 R172 N218 S222 K225 D226 Q229 W302 G303
Catalytic site (residue number reindexed from 1) T63 F64 D67 D71 R141 R156 N202 S206 K209 D210 Q213 W285 G286
Enzyme Commision number 4.2.3.26: R-linalool synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0FV A F76 D79 N218 K225 F64 D67 N202 K209
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016829 lyase activity
GO:0034008 R-linalool synthase activity
GO:0046872 metal ion binding
Biological Process
GO:0033383 geranyl diphosphate metabolic process
GO:0045338 farnesyl diphosphate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5nx5, PDBe:5nx5, PDBj:5nx5
PDBsum5nx5
PubMed28966840
UniProtD5SL78|LNSA_STRCL R-linalool synthase (Gene Name=SCLAV_p1185)

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