Structure of PDB 5nw5 Chain A

Receptor sequence
>5nw5A (length=1085) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
ETRVNPRALEYWVSGEIHGLVDNESVSEFKEIIEGGLGILRQESEDYVAR
RFEVYATFNNIIPILTTKNVNEVDQKFNILIVNIESIIEICIPHLQIAQD
TLLSSSEKKNPFVIRLYVQIVRFFSAIMSNFKIVKWLTKRPDLVNKLKVI
YRWTTGALRNENSNKIIITAQVSFLRDEKFGTFFLSNEEIKPIISTFTEI
MEINSHNLIYEKLLLIRGFLSKYPKLMIETVTSWLPGEVLPRIIIGDEIY
SMKILITSIVVLLELLKKCLDFVDEHERIYQCIMLSPVCETIPEKFLSKL
PLNSYDSANLDKVTIGHLLTQQIKNYIVVKNDNKIAMDLWLSMTGLLYDS
GKRVYDLTSESNKVWFDLNNLCFINNHPKTRLMSIKVWRIITYCICTKIS
QKNQEGNKSLLSLLRTPFQMTLPYVNDPSAREGIIYHLLGVVYTAFTSNK
NLSTDMFELFWDHLITPIYEDYVFKYDSIHLQNVLFTVLHLLIGGKNADV
ALERKHIHPMSVIASEGVKLKDISSLPPQIIKREYDKIMKVVFQAVEVAI
SNVNLAHDLILTSLKHLPEDRKDQTHLESFSSLILKVTQNNKDTPIFRDF
FGAVTSSFVYTFLDLFLRKNDSSLVNFNIQISKVGISQGNMTLDLLKDVI
RKARNETSEFLIIEKFLELDDKKTEVYAQNWVGSTLLPPNISFREFQSLA
NIVNKVPNENSIENFLDLCLKLSFPVNLFTLLHVSMWSNNNFIYFIQSYV
SKNENKLNVDLITLLKTSLPGNPELFSGLLPFLRRNKFMDILEYCIHSNP
NLLNSIPDLNSDLLLKLLPRSRASYFAANIKLFKCSEQLTLVRWLLKGQQ
LEQLNQNFSEIENVLQNASDSELEKSEIIRELLHLAMANPIEPLFSGLLN
FCIKNNMADHLDEFCGNMTSEVLFKISPELLLKLLTYKEKPNGKLLAAVI
EKIENGDDDYILELLEKIIIQKEIQILEKLKEPLLVFFLNPVSSNMQKHK
KSTNMLRELVLLYLTKPLSRSAAKKFFSMLISILPPNPNYQTIDMVNLLI
DLIKSHNRKFKDKRTYNATLKTIGKWIQESGVVHQ
3D structure
PDB5nw5 Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends.
ChainA
Resolution6.502 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K319 K451 K135 K267 PDBbind-CN: Kd=21nM
External links
PDB RCSB:5nw5, PDBe:5nw5, PDBj:5nw5
PDBsum5nw5
PubMed28604726
UniProtP29539|RIF1_YEAST Telomere length regulator protein RIF1 (Gene Name=RIF1)

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