Structure of PDB 5nv2 Chain A

Receptor sequence
>5nv2A (length=133) Species: 9606 (Homo sapiens) [Search protein sequence]
SEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWF
GDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAG
KTFPSSLEDQLKPMLEWAHGGFKPTGIEGLKPN
3D structure
PDB5nv2 Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors
ChainA
Resolution2.029 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9AE A I233 F236 W239 D266 I19 F22 W25 D52
External links
PDB RCSB:5nv2, PDBe:5nv2, PDBj:5nv2
PDBsum5nv2
PubMed
UniProtQ9UBC3|DNM3B_HUMAN DNA (cytosine-5)-methyltransferase 3B (Gene Name=DNMT3B)

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