Structure of PDB 5nuc Chain A

Receptor sequence
>5nucA (length=135) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
LHKEPATLIKAIDGDTCKLMYKGQPMTFRLLLVDTPETKHPKKGVEKYGP
EASAFTKKMVENAKKIEVEFDKGQRTDKYGRGLAYIYADGKMVNEALVRQ
GLAKVAYVYKPNNTHEQHLRKSEAQAKKEKLNIWS
3D structure
PDB5nuc Mobile unnatural amino acid side chains in the core of staphylococcal nuclease.
ChainA
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D21 R35 D40 T41 E43 R87
Catalytic site (residue number reindexed from 1) D15 R29 D34 T35 E37 R81
Enzyme Commision number 3.1.31.1: micrococcal nuclease.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D21 D40 T41 D15 D34 T35
BS02 THP A R35 D83 K84 Y85 R87 L89 Y113 Y115 R29 D77 K78 Y79 R81 L83 Y107 Y109
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:5nuc, PDBe:5nuc, PDBj:5nuc
PDBsum5nuc
PubMed8762134
UniProtP00644|NUC_STAAU Thermonuclease (Gene Name=nuc)

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