Structure of PDB 5nrr Chain A

Receptor sequence
>5nrrA (length=135) Species: 9606 (Homo sapiens) [Search protein sequence]
DSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQ
WFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVR
AGKTFPSSLEDQLKPMLEWAHGGFKPTGIEGLKPN
3D structure
PDB5nrr Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 96E A F236 W239 W263 D266 S297 F24 W27 W51 D54 S85
External links
PDB RCSB:5nrr, PDBe:5nrr, PDBj:5nrr
PDBsum5nrr
PubMed
UniProtQ9UBC3|DNM3B_HUMAN DNA (cytosine-5)-methyltransferase 3B (Gene Name=DNMT3B)

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