Structure of PDB 5nnf Chain A

Receptor sequence
>5nnfA (length=126) Species: 9606 (Homo sapiens) [Search protein sequence]
MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKL
NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKP
GDDIVLMAEALEKLFLQKINELPTEE
3D structure
PDB5nnf Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
ChainA
Resolution1.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W81 V87 L92 L94 Y139 N140 K141 P142 G143 D144 D145 I146 W39 V45 L50 L52 Y97 N98 K99 P100 G101 D102 D103 I104
External links
PDB RCSB:5nnf, PDBe:5nnf, PDBj:5nnf
PDBsum5nnf
PubMed30554943
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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