Structure of PDB 5nne Chain A

Receptor sequence
>5nneA (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPT
3D structure
PDB5nne Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
ChainA
Resolution1.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W81 V87 N93 Y139 D145 M149 W40 V46 N52 Y98 D104 M108
External links
PDB RCSB:5nne, PDBe:5nne, PDBj:5nne
PDBsum5nne
PubMed30554943
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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