Structure of PDB 5nl1 Chain A

Receptor sequence
>5nl1A (length=141) Species: 10090 (Mus musculus) [Search protein sequence]
LTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKMD
ESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEM
SRGVKLLAALLEDEGGNGRPLLQAAKGLAGAVSELLRSAQP
3D structure
PDB5nl1 Shigella IpaA Binding to Talin Stimulates Filopodial Capture and Cell Adhesion.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A K540 V547 V558 T561 P607 A611 L615 A618 E621 S625 K53 V60 V71 T74 P120 A124 L128 A131 E134 S138
BS02 peptide A S556 N559 E567 S69 N72 E80
BS03 peptide A S501 Q504 A505 S14 Q17 A18
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
Cellular Component
GO:0001726 ruffle
GO:0005925 focal adhesion

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:5nl1, PDBe:5nl1, PDBj:5nl1
PDBsum5nl1
PubMed30673614
UniProtP26039|TLN1_MOUSE Talin-1 (Gene Name=Tln1)

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