Structure of PDB 5njk Chain A

Receptor sequence
>5njkA (length=147) Species: 9606 (Homo sapiens) [Search protein sequence]
WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKG
FFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFD
RAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQK
3D structure
PDB5njk A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer.
ChainA
Resolution3.13 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R53 I111 V114 S115 F116 C117 R132 S155 G159 F162 R29 I87 V90 S91 F92 C93 R108 S131 G135 F138
External links
PDB RCSB:5njk, PDBe:5njk, PDBj:5njk
PDBsum5njk
PubMed29269425
UniProtP49757|NUMB_HUMAN Protein numb homolog (Gene Name=NUMB)

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