Structure of PDB 5nj8 Chain A

Receptor sequence
>5nj8A (length=176) Species: 9606 (Homo sapiens) [Search protein sequence]
NPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFF
DVALKGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDV
IHQSVYELIHTEDRAEFQRQLHWPPENSPLMERCFICRLRCLLDSSGFLA
MNFQGKLKYLHGQKPQLALFAIATPL
3D structure
PDB5nj8 Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R40 D65 K66 R7 D32 K33 PDBbind-CN: Kd=90nM
BS02 dna A R38 H39 R42 R5 H6 R9 PDBbind-CN: Kd=90nM
BS03 ER3 A L112 E116 L59 E63
Gene Ontology
Molecular Function
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006805 xenobiotic metabolic process
GO:0009410 response to xenobiotic stimulus

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Molecular Function
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Biological Process
External links
PDB RCSB:5nj8, PDBe:5nj8, PDBj:5nj8
PDBsum5nj8
PubMed28602820
UniProtP35869|AHR_HUMAN Aryl hydrocarbon receptor (Gene Name=AHR)

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