Structure of PDB 5nig Chain A

Receptor sequence
>5nigA (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
KEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRF
ASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELRE
PNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYL
PFLPSTEDVYDCRVEHWGLDEPLLKHWEFD
3D structure
PDB5nig Memory T cells specific to citrullinated alpha-enolase are enriched in the rheumatic joint.
ChainA
Resolution1.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q9 E11 F24 A52 S53 F54 G58 N62 V65 D66 N69 I72 K75 Q8 E10 F23 A51 S52 F53 G57 N61 V64 D65 N68 I71 K74
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5nig, PDBe:5nig, PDBj:5nig
PDBsum5nig
PubMed29853344
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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