Structure of PDB 5nht Chain A

Receptor sequence
>5nhtA (length=197) Species: 9606 (Homo sapiens) [Search protein sequence]
EVEQNSGPLSVPEGAIASLNCTYSDRGSQSFFWYRQYSGKSPELIMSIYS
NGDKEDGRFTAQLNKASQYVSLLIRDSQPSDSATYLCAVGGGADGLTFGK
GTHLIIQPYIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDV
YITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFP
3D structure
PDB5nht human 199.54-16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2
ChainA
Resolution3.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Q31 G93 Q29 G91
Gene Ontology
Molecular Function
GO:0042605 peptide antigen binding
Biological Process
GO:0002250 adaptive immune response
Cellular Component
GO:0005886 plasma membrane
GO:0042101 T cell receptor complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5nht, PDBe:5nht, PDBj:5nht
PDBsum5nht
PubMed
UniProtA0A075B6T6|TVAL2_HUMAN T cell receptor alpha variable 12-2 (Gene Name=TRAV12-2);
K7N5N2

[Back to BioLiP]