Structure of PDB 5ng9 Chain A

Receptor sequence
>5ng9A (length=263) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFK
YKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVI
DFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRS
KIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYI
EQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKL
KNKWWYDKGECGS
3D structure
PDB5ng9 Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.
ChainA
Resolution1.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8VN A Y61 P89 T91 R96 L138 G141 S142 T143 E193 Y61 P89 T91 R96 L138 G141 S142 T143 E193 MOAD: Ki=191nM
PDBbind-CN: -logKd/Ki=6.72,Ki=191nM
BS02 8WQ A Y61 P89 T91 R96 L138 G141 S142 T143 E193 Y61 P89 T91 R96 L138 G141 S142 T143 E193
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5ng9, PDBe:5ng9, PDBj:5ng9
PDBsum5ng9
PubMed28691798
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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