Structure of PDB 5nfp Chain A

Receptor sequence
>5nfpA (length=247) Species: 9606 (Homo sapiens) [Search protein sequence]
PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQMIAAVKWAK
AIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQSSANLLCFAPDLII
NEQRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDG
LKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVV
ENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ
3D structure
PDB5nfp Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V575 K579 R585 L589 M593 Q597 E751 M752 E755 N759 V46 K50 R56 L60 M64 Q68 E222 M223 E226 N230
BS02 8W5 A M560 L563 N564 Q570 M601 M604 F623 M639 M646 C736 T739 M31 L34 N35 Q41 M72 M75 F94 M110 M117 C207 T210
External links
PDB RCSB:5nfp, PDBe:5nfp, PDBj:5nfp
PDBsum5nfp
PubMed28937774
UniProtP04150|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)

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