Structure of PDB 5nf9 Chain A

Receptor sequence
>5nf9A (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB5nf9 Biophysical and structural characterization of mono/di-arylated lactosamine derivatives interaction with human galectin-3.
ChainA
Resolution1.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8VW A H158 R162 E165 N174 W181 E184 R186 H46 R50 E53 N62 W69 E72 R74 MOAD: Kd=4.7uM
PDBbind-CN: -logKd/Ki=5.33,Kd=4.7uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:5nf9, PDBe:5nf9, PDBj:5nf9
PDBsum5nf9
PubMed28554839
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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