Structure of PDB 5nf7 Chain A

Receptor sequence
>5nf7A (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB5nf7 Biophysical and structural characterization of mono/di-arylated lactosamine derivatives interaction with human galectin-3.
ChainA
Resolution1.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 TVD A R162 E184 R186 R50 E72 R74
BS02 GAL A H158 R162 N174 W181 E184 H46 R50 N62 W69 E72
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:5nf7, PDBe:5nf7, PDBj:5nf7
PDBsum5nf7
PubMed28554839
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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