Structure of PDB 5nem Chain A

Receptor sequence
>5nemA (length=589) Species: 9606 (Homo sapiens) [Search protein sequence]
FNLDVDSPAEYSGPEGSYFGFAVDFFVPSSRMFLLVGAPKANTTQPGIVE
GGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQ
DKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQ
GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSI
KYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGM
VYIYDGKNMSSYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDR
GSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQD
GFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSCPPS
FGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSI
LNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLK
GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPI
TIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILL
3D structure
PDB5nem Rules of engagement between alpha v beta 6 integrin and foot-and-mouth disease virus.
ChainA
Resolution10.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D415 N417 Y419 D421 A437 D412 N414 Y416 D418 A434
BS02 CA A D349 D351 D353 F355 D357 D346 D348 D350 F352 D354
BS03 CA A D230 N232 D234 I236 D238 D228 N230 D232 I234 D236
BS04 CA A D284 N286 D288 Y290 D292 D281 N283 D285 Y287 D289
Gene Ontology
Cellular Component
GO:0008305 integrin complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5nem, PDBe:5nem, PDBj:5nem
PDBsum5nem
PubMed28534487
UniProtP06756|ITAV_HUMAN Integrin alpha-V (Gene Name=ITGAV)

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