Structure of PDB 5neb Chain A

Receptor sequence
>5nebA (length=256) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFL
YDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVID
FSKPFMTLGISILYRKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSK
ISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQR
NCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKW
WRGNGC
3D structure
PDB5neb Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8VE A Y61 P88 T90 R95 G140 S141 T142 E190 Y61 P88 T90 R95 G140 S141 T142 E190 MOAD: Ki=17nM
PDBbind-CN: -logKd/Ki=7.77,Ki=17nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5neb, PDBe:5neb, PDBj:5neb
PDBsum5neb
PubMed28691798
UniProtP22756|GRIK1_RAT Glutamate receptor ionotropic, kainate 1 (Gene Name=Grik1)

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