Structure of PDB 5ncv Chain A

Receptor sequence

>5ncvA (length=104) Species: 559292 (Saccharomyces cerevisiae S288C)

AGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEGYSYT
DANIKKNVLWDENNMSEYLTNPKKYIPGTKMAFGGLKKEKDRNDLITYLK
KATE

3D structure

• PDB: 5ncv Phosphonated Calixarene as a ""Molecular Glue"" for Protein Crystallization
• Chain: A
• Resolution: 1.5 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEC	A	R13 C14 C17 H18 G29 I35 S40 G41 Y46 Y48 T49 N52 W59 M64 Y67 L68 T78 K79 M80 F82	R14 C15 C18 H19 G30 I36 S41 G42 Y47 Y49 T50 N53 W60 M65 Y68 L69 T79 K80 M81 F83
BS02	8TE	A	D50 A51 K54	D51 A52 K55
BS03	8TE	A	N70 K86	N71 K87

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0009055 electron transfer activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:1901612 cardiolipin binding

Biological Process

• GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
• GO:0006123 mitochondrial electron transport, cytochrome c to oxygen

Cellular Component

• GO:0005739 mitochondrion
• GO:0005758 mitochondrial intermembrane space

External links

• PDB: RCSB:5ncv, PDBe:5ncv, PDBj:5ncv
• PDBsum: 5ncv
• UniProt: P00044|CYC1_YEAST Cytochrome c isoform 1 (Gene Name=CYC1)