Structure of PDB 5ncp Chain A

Receptor sequence
>5ncpA (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
EQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRK
IQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFAS
AMMHALEVL
3D structure
PDB5ncp Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EG5 A Y16 W23 K69 N71 F77 Q79 R81 Y14 W21 K67 N69 F75 Q77 R79
External links
PDB RCSB:5ncp, PDBe:5ncp, PDBj:5ncp
PDBsum5ncp
PubMed33184177
UniProtQ8N8S7|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)

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