Structure of PDB 5na1 Chain A

Receptor sequence
>5na1A (length=398) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence]
RKKVLVLGAGYAGLQTVTKLQKAISTEEAEITLINKNEYHYEATWLHEAS
AGTLNYEDVLYPVESVLKKDKVNFVQAEVTKIDRDAKKVETNQGIYDFDI
LVVALGFVSETFGIEGMKDHAFQIENVITARELSRHIEDKFANYAASKEK
DDNDLSILVGGAGFTGVEFLGELTDRIPELCSKYGVDQNKVKITCVEAAP
KMLPMFSEELVNHAVSYLEDRGVEFKIATPIVACNEKGFVVEVDGEKQQL
NAGTSVWAAGVRGSKLMEESFEGVKRGRIVTKQDLTINGYDNIFVIGDCS
AFIPAGEERPLPTTAQIAMQQGESVAKNIKRILNGESTEEFEYVDRGTVC
SLGSHDGVGMVFGKPIAGKKAAFMKKVIDTRAVFKIGGIGLAFKKGKF
3D structure
PDB5na1 The key role of glutamate 172 in the mechanism of type II NADH:quinone oxidoreductase of Staphylococcus aureus.
ChainA
Resolution2.32 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.6.5.9: NADH:ubiquinone reductase (non-electrogenic).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A G14 Y15 A16 N39 K40 A47 T48 E82 V83 L109 G110 F111 F168 G301 D302 T317 T318 A319 G10 Y11 A12 N35 K36 A43 T44 E78 V79 L105 G106 F107 F164 G297 D298 T313 T314 A315
Gene Ontology
Molecular Function
GO:0003955 NAD(P)H dehydrogenase (quinone) activity
GO:0016491 oxidoreductase activity
GO:0050136 NADH:ubiquinone reductase (non-electrogenic) activity
Biological Process
GO:0019646 aerobic electron transport chain
Cellular Component
GO:0005886 plasma membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:5na1, PDBe:5na1, PDBj:5na1
PDBsum5na1
PubMed28801048
UniProtQ2FZV7|NDH_STAA8 Type II NADH:quinone oxidoreductase (Gene Name=SAOUHSC_00878)

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