Structure of PDB 5n70 Chain A

Receptor sequence
>5n70A (length=339) Species: 34613 (Ixodes ricinus) [Search protein sequence]
IHEGPYPEPLVNLLDVVYYGPISIGTPPQDFQVIFDTGSANLWLPSSKCT
TKYCLHHHRYDSSKSSTYEADGRNFTIVYGSGNVEGFISKDVCRIGSAKV
SGQPLGEALVVGGESLLEAPFDGILGLAYPSIAVDGVVPVFDNMMKQGLL
GEQNVFSVYLNRDPSSKEGGEVLFGGIDHDHYKGSITYVPVTAKGYWQFH
VDGVKSVSASKSAPELLCKDGCEAIANTGTSLITGPPEEVDSLNQYLGGT
KTEGGQYLLDCDKLESLPNVTFTISGKEFSLRSKDYVLKVNQQGQTLCVS
GFMGLEMPQPLWILGDVFLGPYYTIFDRDQDRVGFAEVA
3D structure
PDB5n70 Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite.
ChainA
Resolution1.81 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y40 Y41 I117 G118 A120 M166 R184 G191 G192 E193 V194 L195 F196 G197 Y18 Y19 I95 G96 A98 M144 R162 G169 G170 E171 V172 L173 F174 G175
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5n70, PDBe:5n70, PDBj:5n70
PDBsum5n70
PubMed29396291
UniProtV5HCK7

[Back to BioLiP]