Structure of PDB 5n2g Chain A

Receptor sequence
>5n2gA (length=999) Species: 10249 (Vaccinia virus Copenhagen) [Search protein sequence]
GAMDPDVRCINWFESHGENRFLYLKSRCRNGETVFIRFPHYFYYVVTDEI
YQSLSPPPFNARPLGKMRTIDIDETISYNLDIKDRKCSVADMWLIEEPKK
RSIQNATMDEFLNISWFYISNGISPDGCYSLDEQYLTKINNGCYHCDDPR
NCFAKKIPRFDIPRSYLFLDIECHFDKKFPSVFINPISHTSYCYIDLSGK
RLLFTLINEEMLTEQEIQEAVDRGCLRIQSLMEMDYERELVLCSEIVLLR
IAKQLLELTFDYVVTFNGHNFDLRYITNRLELLTGEKIIFRSPDKKEAVH
LCIYERNQSSANTTFHVNNNNGTIFFDLYSFIQKSEKLDSYKLDSISKNA
FSCMGKVLNRGVREMTFIGDDTTDAKGKAAAFAKVLTTGNYVTVDEDIIC
KVIRKDIWENGFKVVLLCPTLPNDTYKLSFGKDDVDLAQMYKDYNLNIAL
DMARYCIHDACLCQYLWEYYGVETKTDAGASTYVLPQSMVFEYRASTVIK
GPLLKLLLETKTILVRSETKQKFPYEGGKVFAPKQKMFSNNVLIFDYNSL
YPNVCIFGNLSPETLVGVVVSTNRLEEEINNQLLLQKYPPPRYITVHCEP
RLPNLISEIAIFDRSIEGTIPRLLRTFLAERARYKKMLKQATSSTEKAIY
DSMQYTYKIVANSVYGLMGFRNSALYSYASAKSCTSIGRRMILYLESVLN
GAELSNGMLRFANPLSNPFYMDDRDINPIVKTSLPIDYRFRFRSVYGDTD
SVFTEIDSQDVDKSIEIAKELERLINNRVLFNNFKIEFEAVYKNLIMQSK
KKYTTMKYSASSNSKSVPERINKGTSETRRDVSKFHKNMIKTYKTRLSEM
LSEGRMNSNQVCIDILRSLETDLRSEFDSRSSPLELFMLSRMHHSNYDNP
NMYLVTEYNKNNPETIELGERYYFAYICPANVPWTKKLVNIKTYETIIDR
SFKLGSDQRIFYEVYFKRLTSEIVNLLDNKVLCISFFERMFGSKPTFYE
3D structure
PDB5n2g The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding.
ChainA
Resolution2.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D166 E168 D462 D170 E172 D459
BS02 MN A D166 D268 D170 D272
BS03 MN A D549 E790 E792 D546 E787 E789
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006310 DNA recombination
GO:0039693 viral DNA genome replication

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:5n2g, PDBe:5n2g, PDBj:5n2g
PDBsum5n2g
PubMed29129932
UniProtP20509|DPOL_VACCC DNA polymerase (Gene Name=OPG071)

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