Structure of PDB 5n2f Chain A

Receptor sequence
>5n2fA (length=126) Species: 9606 (Homo sapiens) [Search protein sequence]
AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQF
VHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMIS
YGGADYKRITVKVNAPYAAALEHHHH
3D structure
PDB5n2f Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8HW A Y56 M115 A121 D122 Y39 M98 A104 D105 PDBbind-CN: -logKd/Ki=7.10,IC50=80nM
External links
PDB RCSB:5n2f, PDBe:5n2f, PDBj:5n2f
PDBsum5n2f
PubMed28613862
UniProtQ9NZQ7|PD1L1_HUMAN Programmed cell death 1 ligand 1 (Gene Name=CD274)

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