Structure of PDB 5n29 Chain A

Receptor sequence
>5n29A (length=265) Species: 679716 (Trypanosoma brucei gambiense DAL972) [Search protein sequence]
TVRIAFVGKYLQDAGDTYFSVLQCFEHCQIALQVRLDILYVDSEELEGPN
ADEARKALLGCDGIFVPGGFGNRGVDGKCAAAQVARMNNIPYFGVCLGMQ
VAVIELSRNVVGWSDANSEEFNKESTHQVVRIMDCDRNKMGANMHLGACD
VYIVEKSSIMAKIYSKSNIVVERHRHRYEVNTAYFEDLRKAGLCISAVTD
PTFSSRCRVEAVENPSLRFFLAVQFHPEFISTPMDPAPTYLSFMAAAAKK
DYVWPQKCSQRRLKQ
3D structure
PDB5n29 An Improved Model of the Trypanosoma brucei CTP Synthetase Glutaminase Domain-Acivicin Complex.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.4.2: CTP synthase (glutamine hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CL A K485 F542 K162 F219
BS02 CL A G331 R396 K401 G8 R73 K78
Gene Ontology
Molecular Function
GO:0003883 CTP synthase activity
Biological Process
GO:0006221 pyrimidine nucleotide biosynthetic process
GO:0006241 CTP biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5n29, PDBe:5n29, PDBj:5n29
PDBsum5n29
PubMed28333400
UniProtC9ZI73

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