Structure of PDB 5n1y Chain A

Receptor sequence
>5n1yA (length=277) Species: 9606 (Homo sapiens) [Search protein sequence]
MGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRA
PWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMY
GCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEA
AHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEA
TLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVV
PSGQEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB5n1y Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
ChainA
Resolution1.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 E63 K66 H70 T73 D77 Y84 Y99 T143 W147 L156 Y159 W167 Y171 Y8 E64 K67 H71 T74 D78 Y85 Y100 T144 W148 L157 Y160 W168 Y172
External links
PDB RCSB:5n1y, PDBe:5n1y, PDBj:5n1y
PDBsum5n1y
PubMed27183389
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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