Structure of PDB 5mzv Chain A

Receptor sequence
>5mzvA (length=303) Species: 9606 (Homo sapiens) [Search protein sequence]
IWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITWTLDQSSEVLGSG
KTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKE
PKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGA
ATLSAERVRGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKLKYEN
YTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLT
FCVQVQGKREKKDRVFTDKTSATVICRKNASISVRAQDRYYSSSWSEWAS
VPC
3D structure
PDB5mzv Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN A W24 E25 W2 E3
Gene Ontology
Molecular Function
GO:0004896 cytokine receptor activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5mzv, PDBe:5mzv, PDBj:5mzv
PDBsum5mzv
PubMed29287995
UniProtP29460|IL12B_HUMAN Interleukin-12 subunit beta (Gene Name=IL12B)

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