Structure of PDB 5mzn Chain A

Receptor sequence
>5mznA (length=682) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
ELAKQELEHMRKRLNVDMNPLYEIILQWDYTRNSEYPDDEPIGNYSDVKD
FFNSPADYQKVMKPLLLLESWQGLCSSRDREDYKPFSIIVGNRTAVSDFY
DVYASVAKQVIQDCGISESDLIVMAYLPDFRPDKRLSSDDFKKAQHTCLA
KVRTLKNTKGGNVDVTLRIHRNHSFSKFLTLRSEIYCVKVMQMTTIEREY
STLEGLEYYDLVGQILQAKPSPPVNVDAAEIETVKKSYKLNTSQAEAIVN
SVSKEGFSLIQGPPGTGKTKTILGIIGYFLSTKNASNTEQLLKKQKILIC
APSNAAVDEICLRLKSGVYDKQGHQFKPQLVRVGRSDVVNVAIKDLTLEE
LVDKRIGERNYNYRNRDLDRRNAQAHILAVSDIICSTLSGSAHDVLATMG
IKFDTVIIDEACQCTELSSIIPLRYGGKRCIMVGDPNQLPPTVLSGAASN
FKYNQSLFVRMEKNSSPYLLDVQYRMHPSISKFPSSEFYQGRLKDGPGMD
ILNKRPWHQLEPLAPYKFFDIISMSYTNMEEIRVAIELVDYLFRKFDNKI
DFTGKIGIISPYREQMQKMRKEFARYFGGMINKSIDFNTIDGFQGQEKEI
ILISCVRAKSSVGFLKDFRRMNVALTRAKTSIWVLGHQRSLAKSKLWRDL
IEDAKDRSCLAYACSGFLDPRNNRAQSILRKF
3D structure
PDB5mzn Sen1 has unique structural features grafted on the architecture of the Upf1-like helicase family.
ChainA
Resolution1.787 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A Q1339 G1362 K1363 T1364 K1365 R1422 Y1655 Q244 G267 K268 T269 K270 R313 Y474
Gene Ontology
Molecular Function
GO:0004386 helicase activity

View graph for
Molecular Function
External links
PDB RCSB:5mzn, PDBe:5mzn, PDBj:5mzn
PDBsum5mzn
PubMed28408439
UniProtQ00416|SEN1_YEAST Helicase SEN1 (Gene Name=SEN1)

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