Structure of PDB 5mxh Chain A

Receptor sequence
>5mxhA (length=346) Species: 553480 (Photorhabdus asymbiotica subsp. asymbiotica ATCC 43949) [Search protein sequence]
MQPIALSEIVSVVNTSDGRLEVFGVGTDKAVWHNRQMAPHTGSPWSGWSS
LKGQVTSKPVVYINTDGRLEVFARGTDNALWHIWQTATNAGWSNWQSLGG
VITSNPAIYANTDGRLEVFARGADNALWHISQTTAHSGPWSSWASLNGVI
TSNPTVHINSDGRLEVFARGTDNALWHIWQTAPDSNLWSSWESLNGIITS
DPVVIDTADGRLEVFARGADNALWHIWQTISHSGPWSGWQSLNGVITSAP
AVAKNCDNRLEAFARGTDNALWHTWQTVSHSGPWSSWQSLNGVITSAPTA
VRDADGRLEVFARGTDNALWLTWQTASSWSPWISLGGVLIDASAIK
3D structure
PDB5mxh Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GAL A R91 E93 H105 W107 G161 W163 R68 E70 H82 W84 G138 W140 MOAD: ic50=377.96mM
BS02 GAL A R186 E188 W202 G257 W259 R163 E165 W179 G234 W236 MOAD: ic50=377.96mM
BS03 GAL A R282 E284 H296 W298 Q347 W352 R259 E261 H273 W275 Q324 W329 MOAD: ic50=377.96mM
BS04 MG A N37 T38 N14 T15
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5mxh, PDBe:5mxh, PDBj:5mxh
PDBsum5mxh
PubMed28806750
UniProtC7BLE4

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