Structure of PDB 5mw2 Chain A

Receptor sequence
>5mw2A (length=122) Species: 9606 (Homo sapiens) [Search protein sequence]
SQIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGL
FYSIFTDQLKRNLSVINLDPEINPEGFNILLDFMYTSRLNLREGNIMAVM
ATAMYLQMEHVVDTCRKFIKAS
3D structure
PDB5mw2 Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6.
ChainA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 U52 A M51 A52 C53 G55 Y58 F89 Q113 M114 E115 H116 V117 M45 A46 C47 G49 Y52 F83 Q107 M108 E109 H110 V111 MOAD: ic50<3nM
PDBbind-CN: -logKd/Ki=8.52,IC50<3nM
External links
PDB RCSB:5mw2, PDBe:5mw2, PDBj:5mw2
PDBsum5mw2
PubMed28930682
UniProtP41182|BCL6_HUMAN B-cell lymphoma 6 protein (Gene Name=BCL6)

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