Structure of PDB 5muc Chain A

Receptor sequence
>5mucA (length=158) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPE
TITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTD
KPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYA
NNDVVVPT
3D structure
PDB5muc KinITC-One Method Supports both Thermodynamic and Kinetic SARs as Exemplified on FimH Antagonists.
ChainA
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AH2 A F1 I13 N46 D47 D54 Q133 N135 D140 F1 I13 N46 D47 D54 Q133 N135 D140 PDBbind-CN: -logKd/Ki=6.04,Kd=0.913uM
Gene Ontology
Cellular Component
GO:0009289 pilus

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5muc, PDBe:5muc, PDBj:5muc
PDBsum5muc
PubMed29939458
UniProtP08191|FIMH_ECOLI Type 1 fimbrin D-mannose specific adhesin (Gene Name=fimH)

[Back to BioLiP]