Structure of PDB 5mr8 Chain A

Receptor sequence
>5mr8A (length=186) Species: 9606 (Homo sapiens) [Search protein sequence]
PNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDI
GKPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQE
PVPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKN
CERFNEADSEVAQAGKAVALYFEDKLTEIYSDRTFA
3D structure
PDB5mr8 Crystal structure of TRIM33 PHD-Bromodomain isoform B in complex with H3K9ac histone peptide
ChainA
Resolution1.74 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N886 E887 N895 G896 G897 D898 L899 C901 E903 H910 P922 G924 N2 E3 N11 G12 G13 D14 L15 C17 E19 H26 P38 G40
BS02 ZN A C890 C893 H910 C913 C6 C9 H26 C29
BS03 ZN A C902 C905 C928 C931 C18 C21 C44 C47
External links
PDB RCSB:5mr8, PDBe:5mr8, PDBj:5mr8
PDBsum5mr8
PubMed
UniProtQ9UPN9|TRI33_HUMAN E3 ubiquitin-protein ligase TRIM33 (Gene Name=TRIM33)

[Back to BioLiP]