Structure of PDB 5mpg Chain A

Receptor sequence
>5mpgA (length=97) Species: 9606 (Homo sapiens) [Search protein sequence]
ASKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPN
TKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQR
3D structure
PDB5mpg Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A A1 S2 K15 F17 G19 G20 L21 F23 D42 V44 M46 R55 G56 F57 F59 R82 E85 K87 A89 V90 R92 S95 R97 A1 S2 K15 F17 G19 G20 L21 F23 D42 V44 M46 R55 G56 F57 F59 R82 E85 K87 A89 V90 R92 S95 R97 PDBbind-CN: Kd=292nM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:5mpg, PDBe:5mpg, PDBj:5mpg
PDBsum5mpg
PubMed28650318
UniProtP09651|ROA1_HUMAN Heterogeneous nuclear ribonucleoprotein A1 (Gene Name=HNRNPA1)

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