Structure of PDB 5mnv Chain A

Receptor sequence
>5mnvA (length=397) Species: 1890 (Streptomyces antibioticus) [Search protein sequence]
ADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMSD
ARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGK
AFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICEL
LGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRDA
PTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLL
LTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTVT
VRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGAQ
LGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW
3D structure
PDB5mnv Substrate-induced conformational change in cytochrome P450 OleP.
ChainA
Resolution2.97 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S180 A244 E247 T248 S249 S292 C356 I357 G358 E365 I397
Catalytic site (residue number reindexed from 1) S170 A234 E237 T238 S239 S282 C346 I347 G348 E355 I387
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A V93 L94 H101 R105 L241 A244 G245 T248 Q252 R298 A348 F349 G350 H354 C356 I357 G358 L361 V83 L84 H91 R95 L231 A234 G235 T238 Q242 R288 A338 F339 G340 H344 C346 I347 G348 L351
BS02 DEB A F84 I243 A244 G294 L396 I397 F74 I233 A234 G284 L386 I387
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5mnv, PDBe:5mnv, PDBj:5mnv
PDBsum5mnv
PubMed30207799
UniProtQ59819

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