Structure of PDB 5mjc Chain A

Receptor sequence
>5mjcA (length=148) Species: 10090 (Mus musculus) [Search protein sequence]
RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSP
EDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVR
LSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG
3D structure
PDB5mjc Ligand pathways in neuroglobin revealed by low-temperature photodissociation and docking experiments.
ChainA
Resolution1.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.7.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM A F42 Y44 H64 K67 V68 V71 H96 V101 F106 V109 F40 Y42 H62 K65 V66 V69 H94 V99 F104 V107
BS02 OXY A W133 Y137 W131 Y135
Gene Ontology
Molecular Function
GO:0005092 GDP-dissociation inhibitor activity
GO:0005344 oxygen carrier activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0098809 nitrite reductase activity
Biological Process
GO:0015671 oxygen transport
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5mjc, PDBe:5mjc, PDBj:5mjc
PDBsum5mjc
PubMed31576217
UniProtQ9ER97|NGB_MOUSE Neuroglobin (Gene Name=Ngb)

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