Structure of PDB 5mj5 Chain A

Receptor sequence
>5mj5A (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]
DMPVERILEAELAVEPPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPL
DDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGA
IFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALRE
KVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGD
TPIDTFLMEMLEA
3D structure
PDB5mj5 Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F277 V280 K284 V298 L301 F450 E453 F33 V36 K40 V54 L57 F206 E209
BS02 7O0 A I268 A271 N306 F313 R316 I324 L326 A327 V332 V342 C432 I24 A27 N62 F69 R72 I80 L82 A83 V88 V98 C188
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5mj5, PDBe:5mj5, PDBj:5mj5
PDBsum5mj5
PubMed28691794
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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