Structure of PDB 5mhj Chain A

Receptor sequence
>5mhjA (length=194) Species: 10299 (Human alphaherpesvirus 1 strain 17) [Search protein sequence]
LDADATSGAFYARYRDGYVSGEPWPGAGPPPPGRVLYGGLGDSRPGLWGA
PEAEEARRRFEASGAPAAVWAPELGDAAQQYALITRLLYTPDAEAMGWLQ
NPRVVPGDVALDQACFRISGAARNSSSFITGSVARAVPHLGYAMAAGRFG
WGLAHAAAAVAMSRRYDRAQKGFLLTSLRRAYAPLLARENAALT
3D structure
PDB5mhj The herpes viral transcription factor ICP4 forms a novel DNA recognition complex.
ChainA
Resolution2.117 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A S418 R456 R457 S126 R164 R165
BS02 dna A R415 S417 R123 S125
Gene Ontology
Biological Process
GO:0045893 positive regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:5mhj, PDBe:5mhj, PDBj:5mhj
PDBsum5mhj
PubMed28505309
UniProtP08392|ICP4_HHV11 Major viral transcription factor ICP4 (Gene Name=ICP4)

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