Structure of PDB 5mgm Chain A

Receptor sequence
>5mgmA (length=100) Species: 9606 (Homo sapiens) [Search protein sequence]
LTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLL
RGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFY
3D structure
PDB5mgm Discovery of BAZ2A bromodomain ligands.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7MZ A P1817 F1818 E1820 V1822 V1827 N1873 V1879 P19 F20 E22 V24 V29 N75 V81 PDBbind-CN: -logKd/Ki=3.30,Kd>500uM
BindingDB: Kd=>500000nM
External links
PDB RCSB:5mgm, PDBe:5mgm, PDBj:5mgm
PDBsum5mgm
PubMed28837921
UniProtQ9UIF9|BAZ2A_HUMAN Bromodomain adjacent to zinc finger domain protein 2A (Gene Name=BAZ2A)

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