Structure of PDB 5mgk Chain A

Receptor sequence
>5mgkA (length=103) Species: 9606 (Homo sapiens) [Search protein sequence]
HSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRE
RLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESRWE
EFY
3D structure
PDB5mgk Discovery of BAZ2A bromodomain ligands.
ChainA
Resolution2.301 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7MW A P1817 F1818 V1822 N1873 V1879 P22 F23 V27 N78 V84 MOAD: Kd=100uM
PDBbind-CN: -logKd/Ki=4.00,Kd=100uM
BindingDB: Kd=100000nM
External links
PDB RCSB:5mgk, PDBe:5mgk, PDBj:5mgk
PDBsum5mgk
PubMed28837921
UniProtQ9UIF9|BAZ2A_HUMAN Bromodomain adjacent to zinc finger domain protein 2A (Gene Name=BAZ2A)

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