Structure of PDB 5mgf Chain A

Receptor sequence
>5mgfA (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVI
KKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGH
NMRKYFEKKWTDTFKV
3D structure
PDB5mgf Discovery of BAZ2A bromodomain ligands.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7MW A F1889 V1893 N1944 I1950 F34 V38 N89 I95 MOAD: Kd=54uM
PDBbind-CN: -logKd/Ki=4.27,Kd=54uM
BindingDB: Kd=54000nM
External links
PDB RCSB:5mgf, PDBe:5mgf, PDBj:5mgf
PDBsum5mgf
PubMed28837921
UniProtQ9UIF8|BAZ2B_HUMAN Bromodomain adjacent to zinc finger domain protein 2B (Gene Name=BAZ2B)

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