Structure of PDB 5mge Chain A

Receptor sequence
>5mgeA (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVI
KKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGH
NMRKYFEKKWTDTFKV
3D structure
PDB5mge Discovery of BAZ2A bromodomain ligands.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7MX A P1888 F1889 V1893 V1898 N1944 P33 F34 V38 V43 N89 MOAD: Kd=87uM
PDBbind-CN: -logKd/Ki=4.06,Kd=87uM
BindingDB: Kd=87000nM
External links
PDB RCSB:5mge, PDBe:5mge, PDBj:5mge
PDBsum5mge
PubMed28837921
UniProtQ9UIF8|BAZ2B_HUMAN Bromodomain adjacent to zinc finger domain protein 2B (Gene Name=BAZ2B)

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