Structure of PDB 5mfi Chain A

Receptor sequence

>5mfiA (length=239) Species: 32630 (synthetic construct) [Search protein sequence]

ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQKLIEAGALSPLVKL
LDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEV
IQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAI
ANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNN
EQIQKLEEAGAEPALEKLQSSPNEEVQKNAQAALEALNS

3D structure

PDB

5mfi Curvature of designed armadillo repeat proteins allows modular peptide binding.

Chain

Resolution

1.45 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	G83 N84 N85 I88 N121 S124 G125 N126 N127 E156 W159 N163 S166 G167 N168 N169 I172 W201 N205 S208	G72 N73 N74 I77 N110 S113 G114 N115 N116 E145 W148 N152 S155 G156 N157 N158 I161 W190 N194 S197
BS02	peptide	A	E72 W75 W117 E156	E61 W64 W106 E145

External links

PDB	RCSB:5mfi, PDBe:5mfi, PDBj:5mfi
PDBsum	5mfi
PubMed	28864298

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