Structure of PDB 5mfg Chain A

Receptor sequence

>5mfgA (length=282) Species: 32630 (synthetic construct) [Search protein sequence]

ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQL
LSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQI
LQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWAL
SNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGN
EQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKE
AGALEKLEQLQSHENEKIQKEAQEALEKLQSH

3D structure

PDB

5mfg Curvature of designed armadillo repeat proteins allows modular peptide binding.

Chain

Resolution

1.901 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	A	R33 E72 W75 S78 W117 S120 W159 W201 W243 K260 E261 L265 E266	R22 E61 W64 S67 W106 S109 W148 W190 W232 K249 E250 L254 E255
BS02	CA	A	N21 Q60	N10 Q49
BS03	CA	A	P149 E151	P138 E140
BS04	CA	A	P191 E193	P180 E182
BS05	CA	A	P107 E109	P96 E98
BS06	CA	A	P65 E67	P54 E56
BS07	CA	A	P23 Q25	P12 Q14
BS08	CA	A	P233 E235	P222 E224

External links

PDB	RCSB:5mfg, PDBe:5mfg, PDBj:5mfg
PDBsum	5mfg
PubMed	28864298

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