Structure of PDB 5mf0 Chain A

Receptor sequence
>5mf0A (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
CLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNG
AHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYC
QYAFDLKCDSVCVNPYHYERVVS
3D structure
PDB5mf0 Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors.
ChainA
Resolution3.03 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R38 T77 L78 L82 Q83 V84 A85 K88 R23 T62 L63 L67 Q68 V69 A70 K73
BS02 ZN A C71 C115 C127 H132 C56 C100 C112 H117
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005667 transcription regulator complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5mf0, PDBe:5mf0, PDBj:5mf0
PDBsum5mf0
PubMed29234012
UniProtQ13485|SMAD4_HUMAN Mothers against decapentaplegic homolog 4 (Gene Name=SMAD4)

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