Structure of PDB 5m8i Chain A

Receptor sequence
>5m8iA (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
MGSSHHHHHHSSGLVPRGSHMQKEGPEGANLFIYHLPQEFGDQDILQMFM
PFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRL
KVQLKRSKNDSKPW
3D structure
PDB5m8i Aromatic side-chain conformational switch on the surface of the RNA Recognition Motif enables RNA discrimination.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A Q22 F32 Y34 H35 K59 F61 I62 K70 F72 F74 K98 K101 R106 Q22 F32 Y34 H35 K59 F61 I62 K70 F72 F74 K98 K101 R106 PDBbind-CN: Kd=62uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:5m8i, PDBe:5m8i, PDBj:5m8i
PDBsum5m8i
PubMed28935965
UniProtO95319|CELF2_HUMAN CUGBP Elav-like family member 2 (Gene Name=CELF2)

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