Structure of PDB 5m65 Chain A

Receptor sequence
>5m65A (length=469) Species: 29448 (Bradyrhizobium elkanii) [Search protein sequence]
PGFTDYIVKDIALADFGRKEISLAETEMPGLMATREEYGPKQPLKGARIA
GSLHMTIQTAVLIETLAALGADIRWVSCNIYSTQDHAAAAIAAAGIPVFA
VKGETLTEYWDYTAKLFDWHGGGTPNMILDDGGDATMLVHAGYRAEQGDT
AFLDKPGSEEEEIFYALVKRLLKEKPKGWFAEIAKNIKGVSEETTTGVHR
LYEMANKGTLLFPAINVNDSVTKSKFDNLYGCRESLVDGIRRGTDVMLSG
KVAMVAGFGDVGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYEVVTME
DAAPRADIFVTATGNKDIITIEHMRAMKDRAIVCNIGHFDNEIQIASLRN
LKWTNIKPQVDEIEFPDKHRIIMLSEGRLVNLGNAMGHPSFVMSASFTNQ
TLAQIELFANNKDSKYAKKVYVLPKTLDEKVARLHLAKIGVKLTELRKDQ
ADYIGVKQEGPYKSDHYRY
3D structure
PDB5m65 Crystallographic and SAXS studies ofS-adenosyl-l-homocysteine hydrolase fromBradyrhizobium elkanii.
ChainA
Resolution1.945 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H58 S81 S86 D135 E197 N222 K227 D231 N232 C236 H342 H392 S400 Q404
Catalytic site (residue number reindexed from 1) H54 S77 S82 D131 E193 N218 K223 D227 N228 C232 H338 H388 S396 Q400
Enzyme Commision number 3.13.2.1: adenosylhomocysteinase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0004013 adenosylhomocysteinase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006730 one-carbon metabolic process
GO:0033353 S-adenosylmethionine cycle
GO:0071269 L-homocysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5m65, PDBe:5m65, PDBj:5m65
PDBsum5m65
PubMed28512574
UniProtA0A087WNH6|SAHH_BRAEL Adenosylhomocysteinase (Gene Name=ahcY)

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