Structure of PDB 5m4a Chain A

Receptor sequence
>5m4aA (length=548) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
NPVNRLSRLINTQFWNSLTRRVDLNNVGEIAKDTKIDTPGAKNPRIYVPY
DCPEQYEFYVQASQMHPSLKLEVEYLPKKITAEYVKSVNDTPGLLALAME
EHFNPSTGEKTLIGYPYAVPGGRFNELYGWDSYMMALGLLEANKTDVARG
MVEHFIFEINHYGKILNANRSYYLCRSQPPFLTEMALVVFKKLGGRSNPD
AVDLLKRAFQASIKEYKTVWTASPRLDPETGLSRYHPNGLGIPPETESDH
FDTVLLPYASKHGVTLDEFKQLYNDGKIKEPKLDEFFLHDRGVRESGHDT
TYRFEGVCAYLATIDLNSLLYKYEIDIADFIKEFCDDKYEDPLDHSITTS
AMWKEMAKIRQEKITKYMWDDESGFFFDYNTKIKHRTSYESATTFWALWA
GLATKEQAQKMVEKALPKLEMLGGLAACTERSRIRQWDYPFGWAPHQILA
WEGLRSYGYLTVTNRLAYRWLFMMTKAFVDYNGIVVEKYDVTRGTDPAAT
EGFGWVNASYILGLKYMNSHARRALGACIPPISFFSSLRPQERNLYGL
3D structure
PDB5m4a Molecular basis of the 14-3-3 protein-dependent activation of yeast neutral trehalase Nth1.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.28: alpha,alpha-trehalase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC A N346 R473 N167 R294
BS02 GLC A W309 D310 G476 D478 W708 W130 D131 G297 D299 W505
Gene Ontology
Molecular Function
GO:0004555 alpha,alpha-trehalase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005991 trehalose metabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5m4a, PDBe:5m4a, PDBj:5m4a
PDBsum5m4a
PubMed29087344
UniProtP32356|TREA_YEAST Cytosolic neutral trehalase (Gene Name=NTH1)

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