Structure of PDB 5m3b Chain A

Receptor sequence
>5m3bA (length=228) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
APRVITLSPANTELAFAAGITPVGVSSYSDYPPQAQKIEQVSTLQGMNLE
RIVALKPDLVIAWRGGNAERQVDQLASLGIKVMWVDATSIEQIANALRQL
APWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFLQFGINPPFTSGK
ESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGKIPVIP
LTSDWFERASPRIILAAQQLCNALSQVD
3D structure
PDB5m3b Conformational Change of a Tryptophan Residue in BtuF Facilitates Binding and Transport of Cobinamide by the Vitamin B12 Transporter BtuCD-F.
ChainA
Resolution1.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CBY A P31 A32 Y50 W85 G87 F168 W196 S241 E245 R246 P9 A10 Y28 W63 G65 F146 W174 S203 E207 R208 PDBbind-CN: -logKd/Ki=6.92,Kd=0.12uM
Gene Ontology
Molecular Function
GO:0031419 cobalamin binding
Biological Process
GO:0015889 cobalamin transport
Cellular Component
GO:0042597 periplasmic space

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5m3b, PDBe:5m3b, PDBj:5m3b
PDBsum5m3b
PubMed28128319
UniProtP37028|BTUF_ECOLI Vitamin B12-binding protein (Gene Name=btuF)

[Back to BioLiP]