Structure of PDB 5lyr Chain A

Receptor sequence
>5lyrA (length=349) Species: 657309 (Bacteroides xylanisolvens XB1A) [Search protein sequence]
NNLGTELDYDTFCFYYDWYGSEAIDGQYRHWAHAIAPDPNGGSGQNPGTI
PGTQESIASNFYPQLGRYSSSDPNILTKHMDMFVMARTGVLALTWWNEQD
ETEAKRIGLILDAADKKKIKVCFHLEPYPSRNVQNLRENIVKLITRYGNH
PAFYRKDGKPLFFIYDSYLIEPSEWEKLLSPGGSITIRNTAYDALMIGLW
TSSPTVQRPFILNAHFDGFYTYFAATGFTYGSTPTNWVSMQKWAKENGKI
FIPSVGPGYIDTRIRPWNGSVIRTRTDGQYYDAMYRKAIEAGVSAISITS
FNEWHEGSQIEPAVPYTSSEFTYLDYENREPDYYLTRTAYWVGKFRESK
3D structure
PDB5lyr Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-alpha-1,2-Mannanase.
ChainA
Resolution1.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN A H63 R295 E333 E336 H33 R265 E303 E306 PDBbind-CN: -logKd/Ki=7.89,Kd=0.013uM
BS02 MNM A Y46 W126 H154 E156 Y195 Y252 E333 E336 Y16 W96 H124 E126 Y165 Y222 E303 E306 PDBbind-CN: -logKd/Ki=7.89,Kd=0.013uM
Gene Ontology
Molecular Function
GO:0004559 alpha-mannosidase activity
GO:0016787 hydrolase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5lyr, PDBe:5lyr, PDBj:5lyr
PDBsum5lyr
PubMed27992199
UniProtD6D1V7

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