Structure of PDB 5lyc Chain A

Receptor sequence

>5lycA (length=107) Species: 559292 (Saccharomyces cerevisiae S288C)

EFKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEGY
SYTDANIKKNVLWDENNMSEYLTNPKKYIPGTKMAFGGLKKEKDRNDLIT
YLKKATE

3D structure

• PDB: 5lyc Protein Dimerization on a Phosphonated Calix[6]arene Disc.
• Chain: A
• Resolution: 1.8 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEC	A	C14 C17 H18 V28 G29 P30 I35 S40 Y46 Y48 T49 N52 W59 M64 Y67 L68 T78 K79 M80 F82	C18 C21 H22 V32 G33 P34 I39 S44 Y50 Y52 T53 N56 W63 M68 Y71 L72 T82 K83 M84 F86
BS02	7AZ	A	A3 K4 A7 K11 Y97 K100	A7 K8 A11 K15 Y101 K104

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0009055 electron transfer activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:1901612 cardiolipin binding

Biological Process

• GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
• GO:0006123 mitochondrial electron transport, cytochrome c to oxygen

Cellular Component

• GO:0005739 mitochondrion
• GO:0005758 mitochondrial intermembrane space

External links

• PDB: RCSB:5lyc, PDBe:5lyc, PDBj:5lyc
• PDBsum: 5lyc
• PubMed: 28407337
• UniProt: P00044|CYC1_YEAST Cytochrome c isoform 1 (Gene Name=CYC1)